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CDH12 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P55289
Clone Names 70730038
Peptide ID 70730038
Additional Information
Gene ID 1010
Other Names Cadherin-12, Brain cadherin, BR-cadherin, Neural type cadherin 2, N-cadherin 2, CDH12
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1473b was selected from the C-term region of human CDH12. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDH12
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Brain.
Research Areas
Citations (0)

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CDH12 is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.


Shimoyama,Y., Biochem. J. 349 (PT 1), 159-167 (2000)Chalmers,I.J., Genomics 57 (1), 160-163 (1999)Kremmidiotis,G., Genomics 49 (3), 467-471 (1998)Selig,S., Proc. Natl. Acad. Sci. U.S.A. 94 (6), 2398-2403 (1997)

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$ 80.00
Cat# BP1473b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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