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TMPO Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P42166 |
|---|---|
| Clone Names | 100525189 |
| Gene ID | 7112 |
|---|---|
| Other Names | Lamina-associated polypeptide 2, isoform alpha, Thymopoietin isoform alpha, TP alpha, Thymopoietin-related peptide isoform alpha, TPRP isoform alpha, Thymopoietin, TP, Splenin, Thymopentin, TP5, TMPO, LAP2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TMPO |
|---|---|
| Synonyms | LAP2 |
| Function | May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1. |
| Cellular Location | Nucleus. Chromosome. Note=Expressed diffusely throughout the nucleus |
| Tissue Location | Expressed in many tissues. Most abundant in adult thymus and fetal liver |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene resides in the nucleusand may play a role in the assembly of the nuclear lamina, and thushelp maintain the structural organization of the nuclear envelope.It may function as a receptor for the attachment of lamin filamentsto the inner nuclear membrane. Mutations in this gene areassociated with dilated cardiomyopathy. Alternatively splicedtranscript variants encoding different isoforms have been noted forthis gene.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Craig, D.W., et al. Diabet. Med. 26(11):1090-1098(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Shaklai, S., et al. Eur. J. Cell Biol. 87(5):267-278(2008)
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