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BRDG 1 Antibody (N-term F56) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9ULZ2
Clone Names 70319176
Additional Information
Gene ID 26228
Other Names Signal-transducing adaptor protein 1, STAP-1, BCR downstream-signaling protein 1, Docking protein BRDG1, Stem cell adaptor protein 1, STAP1, BRDG1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1475a was selected from the N-term region of human STAP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name STAP1
Synonyms BRDG1
Function In BCR signaling, appears to function as a docking protein acting downstream of TEC and participates in a positive feedback loop by increasing the activity of TEC.
Cellular Location Nucleus. Cytoplasm. Mitochondrion
Research Areas
Citations (0)
citation

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Background

STAP1 functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity.

References

Ma,J., Atherosclerosis 191 (1), 63-72 (2007)Beausoleil,S.A., Nat. Biotechnol. 24 (10), 1285-1292 (2006)Gstaiger,M., Science 302 (5648), 1208-1212 (2003)Minoguchi,M., J. Biol. Chem. 278 (13), 11182-11189 (2003)

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$ 277.78
Cat# BP1475a
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Availability: 2 weeks
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