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SNRPA Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P09012
Clone Names 100525255
Peptide ID 100525255
Additional Information
Gene ID 6626
Other Names U1 small nuclear ribonucleoprotein A, U1 snRNP A, U1-A, U1A, SNRPA
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.
Cellular Location Nucleus.
Research Areas
Citations (0)

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The protein encoded by this gene associates with stem loopII of the U1 small nuclear ribonucleoprotein, which binds the 5'splice site of precursor mRNAs and is required for splicing. Theencoded protein autoregulates itself by polyadenylation inhibitionof its own pre-mRNA via dimerization and has been implicated in thecoupling of splicing and polyadenylation.


Guan, F., et al. RNA 13(12):2129-2140(2007)Hall-Pogar, T., et al. RNA 13(7):1103-1115(2007)Shajani, Z., et al. J. Mol. Biol. 349(4):699-715(2005)Andersen, J.S., et al. Nature 433(7021):77-83(2005)Jessen, T.H., et al. EMBO J. 10(11):3447-3456(1991)

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$ 80.00
Cat# BP14764c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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