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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TAF15 Antibody (N-term) Blocking Peptide   

TAF15 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q92804
Clone Names 100430337
Peptide ID 100430337
Additional Information
Gene ID 8148
Other Names TATA-binding protein-associated factor 2N, 68 kDa TATA-binding protein-associated factor, TAF(II)68, TAFII68, RNA-binding protein 56, TAF15, RBP56, TAF2N
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TAF15
Synonyms RBP56, TAF2N
Function RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).
Cellular Location Nucleus. Cytoplasm. Note=Shuttles from the nucleus to the cytoplasm
Tissue Location Ubiquitous. Observed in all fetal and adult tissues
Research Areas
Citations (0)

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Initiation of transcription by RNA polymerase II requiresthe activities of more than 70 polypeptides. The protein thatcoordinates these activities is transcription factor IID (TFIID),which binds to the core promoter to position the polymeraseproperly, serves as the scaffold for assembly of the remainder ofthe transcription complex, and acts as a channel for regulatorysignals. TFIID is composed of the TATA-binding protein (TBP) and agroup of evolutionarily conserved proteins known as TBP-associatedfactors or TAFs. TAFs may participate in basal transcription, serveas coactivators, function in promoter recognition or modify generaltranscription factors (GTFs) to facilitate complex assembly andtranscription initiation. This gene encodes a subunit of TFIIDpresent in a subset of TFIID complexes. Translocations involvingchromosome 17 and chromosome 9, where the gene for the nuclearreceptor CSMF is located, result in a gene fusion product that isan RNA binding protein associated with a subset of extraskeletalmyxoid chondrosarcomas. Two transcripts encoding different isoformshave been identified.


Rose, J. Phd, et al. Mol. Med. (2010) In press :Schatz, N., et al. Cancer Res. 70(1):398-408(2010)Alves, J., et al. Biochem. Biophys. Res. Commun. 384(4):495-500(2009)Jobert, L., et al. EMBO Rep. 10(5):494-500(2009)Jobert, L., et al. Exp. Cell Res. 315(7):1273-1286(2009)

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$ 80.00
Cat# BP14800a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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