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VEGFB Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P49765 |
|---|---|
| Clone Names | 100507116 |
| Gene ID | 7423 |
|---|---|
| Other Names | Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF, VEGFB, VRF |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | VEGFB |
|---|---|
| Synonyms | VRF |
| Function | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. |
| Cellular Location | Secreted. Note=Secreted but remains associated to cells or to the extracellular matrix unless released by heparin |
| Tissue Location | Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Vascular endothelial growth factor B (VEGFB) signals viathe endothelial receptor VEGFR1 (MIM 165070) and is a regulator ofblood vessel physiology, with a role in endothelial targeting oflipids to peripheral tissues (summarized by Hagberg et al., 2010[PubMed 20228789]).
References
Iyer, S., et al. J. Biol. Chem. 285(31):23779-23789(2010)Romero, R., et al. Am. J. Obstet. Gynecol. (2010) In press :Bailey, S.D., et al. Diabetes Care (2010) In press :Van Hee, V.C., et al. Environ. Health Perspect. 118(7):962-969(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
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