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Mouse Eef2k Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O08796
Clone Names 110316136
Additional Information
Gene ID 13631
Other Names Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, Eef2k
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Eef2k
Function Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation (PubMed:9144159, PubMed:34815424). Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive (PubMed:9144159, PubMed:34815424). In turn, the rate of protein synthesis is reduced (PubMed:9144159, PubMed:34815424).
Tissue Location Ubiquitously expressed (PubMed:9144159). Particularly abundant in skeletal muscle and heart (PubMed:9144159)
Research Areas
Citations (0)
citation

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Background

Phosphorylates eukaryotic elongation factor-2. Binds calmodulin (By similarity).

References

Khan, A.A., et al. Am. J. Pathol. 177(1):481-492(2010)Shen, Q., et al. Parkinsonism Relat. Disord. 15(7):525-531(2009)Py, B.F., et al. Autophagy 5(3):393-396(2009)Im, H.I., et al. PLoS ONE 4 (10), E7424 (2009) :Crawley, S.W., et al. Biochim. Biophys. Acta 1784(6):908-915(2008)

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$ 277.78
Cat# BP14838a
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