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ZDHHC6 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H6R6 |
|---|---|
| Other Accession | NP_071939.1 |
| Clone Names | 100416272 |
| Gene ID | 64429 |
|---|---|
| Other Names | Palmitoyltransferase ZDHHC6, Transmembrane protein H4, Zinc finger DHHC domain-containing protein 6, DHHC-6, Zinc finger protein 376, ZDHHC6, ZNF376 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ZDHHC6 (HGNC:19160) |
|---|---|
| Function | Endoplasmic reticulum palmitoyl acyltransferase that mediates palmitoylation of proteins such as AMFR, CALX, ITPR1 and TFRC (PubMed:22314232, PubMed:22728137, PubMed:25368151, PubMed:28826475). Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins (PubMed:22314232). Mediates palmitoylation of AMFR, promoting AMFR distribution to the peripheral endoplasmic reticulum (PubMed:22728137). Together with SELENOK, palmitoylates ITPR1 in immune cells, leading to regulate ITPR1 stability and function (PubMed:25368151). Stearoyltransferase that mediates stearoylation of TFRC to inhibit TFRC-mediated activation of the JNK pathway and mitochondrial fragmentation (PubMed:26214738). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=When not palmitoylated, accumulates to dot-like structures in the endoplasmic reticulum (PubMed:28826475) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Yang, W., et al. Mol. Cell Proteomics 9(1):54-70(2010)
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