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RAP1B Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P61224
Clone Names 100525234
Peptide ID 100525234
Additional Information
Gene ID 5908
Other Names Ras-related protein Rap-1b, GTP-binding protein smg p21B, RAP1B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAP1B
Function GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function.
Cellular Location Cell membrane. Cytoplasm, cytosol. Cell junction. Note=May shuttle between plasma membrane and cytosol Presence of KRIT1 and CDH5 is required for its localization to the cell junction
Research Areas
Citations (0)

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RAP1B and RAP1A (MIM 179520) belong to a superfamily ofRAS (see MIM 190020)-like small GTP-binding proteins involved incell signaling.


Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)Malchinkhuu, E., et al. Mol. Biol. Cell 20(24):5156-5165(2009)Edreira, M.M., et al. J. Biol. Chem. 284(40):27480-27486(2009)Matsuse, M., et al. Endocr. J. 56(1):161-164(2009)Li, Y.H., et al. J. Biol. Chem. 283(48):33784-33792(2008)

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$ 80.00
Cat# BP14852b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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