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ECSIT Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BQ95
Clone Names 100517253
Peptide ID 100517253
Additional Information
Gene ID 51295
Other Names Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, Protein SITPEC, ECSIT
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ECSIT
Function Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity).
Cellular Location Cytoplasm. Nucleus. Mitochondrion
Research Areas
Citations (0)

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Background

Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.

References

Vogel, R.O., et al. Genes Dev. 21(5):615-624(2007)Xiao, C., et al. Genes Dev. 17(23):2933-2949(2003)Kopp, E., et al. Genes Dev. 13(16):2059-2071(1999)

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$ 80.00
Cat# BP14858b
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