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SND1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7KZF4
Clone Names 100525287
Additional Information
Gene ID 27044
Other Names Staphylococcal nuclease domain-containing protein 1, 100 kDa coactivator, EBNA2 coactivator p100, Tudor domain-containing protein 11, p100 co-activator, SND1, TDRD11
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SND1
Synonyms TDRD11
Function Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (PubMed:28546213, PubMed:18453631). As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (PubMed:28546213). Functions as a bridging factor between STAT6 and the basal transcription factor (PubMed:12234934). Plays a role in PIM1 regulation of MYB activity (PubMed:9809063). Functions as a transcriptional coactivator for STAT5 (By similarity).
Cellular Location Cytoplasm. Nucleus. Melanosome Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus (PubMed:12234934). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065)
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)
citation

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Background

SND1 functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Holt, R., et al. Eur. J. Hum. Genet. 18(9):1013-1019(2010)Gao, X., et al. FEBS Lett. 584(16):3525-3532(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :dit Frey, N.F., et al. Plant Cell 22(5):1575-1591(2010)

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$ 277.78
Cat# BP14873c
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