|Other Names||Protein transport protein Sec61 subunit beta, SEC61B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Necessary for protein translocation in the endoplasmic reticulum.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The Sec61 complex is the central component of the proteintranslocation apparatus of the endoplasmic reticulum (ER) membrane.Oligomers of the Sec61 complex form a transmembrane channel whereproteins are translocated across and integrated into the ERmembrane. This complex consists of three membrane proteins- alpha,beta, and gamma. This gene encodes the beta-subunit protein. TheSec61 subunits are also observed in the post-ER compartment,suggesting that these proteins can escape the ER and recycle back.There is evidence for multiple polyadenylated sites for thistranscript.
Liao, H.J., et al. Cancer Res. 69(15):6179-6183(2009)Wang, B., et al. Cell 133(6):1080-1092(2008)Liao, H.J., et al. Mol. Biol. Cell 18(3):1064-1072(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.