HDAC11 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96DB2 |
---|---|
Clone Names | 100517324 |
Gene ID | 79885 |
---|---|
Other Names | Histone deacetylase 11, HD11, HDAC11 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | HDAC11 |
---|---|
Function | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. |
Cellular Location | Nucleus. |
Tissue Location | Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a class IV histone deacetylase. Theencoded protein is localized to the nucleus and may be involved inregulating the expression of interleukin 10. Alternative splicingresults in multiple transcript variants.
References
Janssen, C., et al. J. Neuropathol. Exp. Neurol. 69(6):573-581(2010)Glozak, M.A., et al. J. Biol. Chem. 284(17):11446-11453(2009)Georgopoulos, K. Nat. Immunol. 10(1):13-14(2009)Villagra, A., et al. Nat. Immunol. 10(1):92-100(2009)Fournel, M., et al. Mol. Cancer Ther. 7(4):759-768(2008)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.