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Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q60700 |
|---|---|
| Clone Names | 110316226 |
| Peptide ID | 110316226 |
| Gene ID | 26404 |
|---|---|
| Other Names | Mitogen-activated protein kinase kinase kinase 12, Dual leucine zipper bearing kinase, DLK, Leucine-zipper protein kinase, ZPK, MAPK-upstream kinase, MUK, Mixed lineage kinase, Map3k12, Zpk |
| Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | Map3k12 |
|---|---|
| Synonyms | Zpk |
| Function | May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro. |
| Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein |
| Tissue Location | Expressed in brain, kidney, lung, heart, testis, gastrointestinal tract, stomach, liver and pancreas Within the nervous system, predominantly expressed in neurons and enriched in synaptic terminals |
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Provided below are standard protocols that you may find useful for product applications.
Background
Map3k12 may be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro.
References
Hirose, Y., et al. Exp. Cell Res. 315(15):2648-2657(2009)Saiga, T., et al. Mol. Cell. Biol. 29(13):3529-3543(2009)Itoh, A., et al. Biochem. Biophys. Res. Commun. 383(2):258-262(2009)Daviau, A., et al. Cell. Signal. 21(4):577-587(2009)Couture, J.P., et al. PLoS ONE 4 (3), E4743 (2009) :
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