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LHX6 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9UPM6 |
|---|---|
| Clone Names | 100517198 |
| Gene ID | 26468 |
|---|---|
| Other Names | LIM/homeobox protein Lhx6, LIM homeobox protein 6, LIM/homeobox protein Lhx61, LHX6, LHX61 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | LHX6 |
|---|---|
| Synonyms | LHX6.1 |
| Function | Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex (By similarity). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of a large protein family thatcontains the LIM domain, a unique cysteine-rich zinc-bindingdomain. The encoded protein may function as a transcriptionalregulator and may be involved in the control of differentiation anddevelopment of neural and lymphoid cells. Two alternatively splicedtranscript variants encoding distinct isoforms have been describedfor this gene. Alternatively spliced transcript variants have beenidentified, but their biological validity has not been determined.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Jung, S., et al. Oncol. Rep. 23(6):1675-1682(2010)Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)Estecio, M.R., et al. Oncogene 25(36):5018-5026(2006)Humphray, S.J., et al. Nature 429(6990):369-374(2004)
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