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PMS1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P54277 |
|---|---|
| Clone Names | 100525261 |
| Gene ID | 5378 |
|---|---|
| Other Names | PMS1 protein homolog 1, DNA mismatch repair protein PMS1, PMS1, PMSL1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PMS1 |
|---|---|
| Synonyms | PMSL1 |
| Function | Probably involved in the repair of mismatches in DNA. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein belonging to the DNA mismatchrepair mutL/hexB family. This protein is thought to be involved inthe repair of DNA mismatches, and it can form heterodimers withMLH1, a known DNA mismatch repair protein. Mutations in this genecause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3)either alone or in combination with mutations in other genesinvolved in the HNPCC phenotype, which is also known as Lynchsyndrome.
References
Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)Adeyemo, A., et al. PLoS Genet. 5 (7), E1000564 (2009) :
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