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TBX3 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O15119
Clone Names 100525279
Peptide ID 100525279
Additional Information
Gene ID 6926
Other Names T-box transcription factor TBX3, T-box protein 3, TBX3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBX3
Function Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00201}
Tissue Location Widely expressed.
Research Areas
Citations (0)

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This gene is a member of a phylogenetically conservedfamily of genes that share a common DNA-binding domain, the T-box.T-box genes encode transcription factors involved in the regulationof developmental processes. This protein is a transcriptionalrepressor and is thought to play a role in the anterior/posterioraxis of the tetrapod forelimb. Mutations in this gene causeulnar-mammary syndrome, affecting limb, apocrine gland, tooth,hair, and genital development. Alternative splicing of this generesults in three transcript variants encoding different isoforms;however, the full length nature of one variant has not beendetermined.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)Christoffels, V.M., et al. Circ. Res. 106(2):240-254(2010)Pfeufer, A., et al. Nat. Genet. 42(2):153-159(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 80.00
Cat# BP14976c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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