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LASP1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q14847
Clone Names 100528126
Peptide ID 100528126
Additional Information
Gene ID 3927
Other Names LIM and SH3 domain protein 1, LASP-1, Metastatic lymph node gene 50 protein, MLN 50, LASP1, MLN50
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LASP1
Synonyms MLN50
Function Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).
Cellular Location Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Associated with the F- actin rich cortical cytoskeleton.
Research Areas
Citations (0)

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Background

This gene encodes a member of a LIM protein subfamilycharacterized by a LIM motif and a domain of Src homology region 3.The encoded protein functions as an actin-binding protein andpossibly in cytoskeletal organization.

References

Traenka, C., et al. Cancer Res. 70(20):8003-8014(2010)Zhao, L., et al. FEBS J. 277(20):4195-4204(2010)Zhao, L., et al. Gut 59(9):1226-1235(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Frietsch, J.J., et al. Br. J. Cancer 102(11):1645-1653(2010)

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$ 80.00
Cat# BP14992c
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