|Other Names||Mitochondrial import receptor subunit TOM22 homolog, hTom22, 1C9-2, Translocase of outer membrane 22 kDa subunit homolog, TOMM22, TOM22|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore.|
|Cellular Location||Mitochondrion outer membrane; Single-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is an integral membraneprotein of the mitochondrial outer membrane. The encoded proteininteracts with TOMM20 and TOMM40, and forms a complex with severalother proteins to import cytosolic preproteins into themitochondrion.
Bellot, G., et al. Cell Death Differ. 14(4):785-794(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)Humphries, A.D., et al. J. Biol. Chem. 280(12):11535-11543(2005)
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