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Phospho-ATRIP(S239) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8WXE1
Other Accession Q9N077, NP_115542.2
Additional Information
Gene ID 84126
Other Names ATR-interacting protein, ATM and Rad3-related-interacting protein, ATRIP, AGS1
Target/Specificity The synthetic peptide sequence is selected from aa 234-248 of HUMAN ATRIP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms AGS1
Function Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Cellular Location Nucleus. Note=Redistributes to discrete nuclear foci upon DNA damage
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.


Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)
Myers, J.S., et al. Cancer Res. 67(14):6685-6690(2007)
Venere, M., et al. Cancer Res. 67(13):6100-6105(2007)

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$ 80.00
$ 99.00
Cat# BP15000a
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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