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Mouse TLR5 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9JLF7
Clone Names 2110810
Peptide ID 2110810
Additional Information
Gene ID 53791
Other Names Toll-like receptor 5, Tlr5
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1505b was selected from the C-term region of human Mouse TLR5 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tlr5
Function Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in liver. Detected in lung and at very low levels in most other tissues
Research Areas
Citations (0)

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TLR5, a Type I membrane protein belonging to the Toll-like receptor family, participates in the innate immune response to microbial agents. It also plays a role in mediating detection of bacterial flagellins. TLR5 acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein binds to TIRAP and MyD88 via their respective TIR domains TLR5 is highly expressed in liver, and is detected in lung and at very low levels in most other tissues. The TLR5 gene lies in a locus that is associated with susceptibility to Salmonella. Inbred strains of mice can be classified into 3 categories according to their resistance to infection with S.typhimurium: susceptible (BALB/c, C57BL/6, C3H/He), intermediate (DBA/2, C75L) and resistant (A, CBA). The strain MOLF/Ei is highly susceptible to the infection, has an unique TLR5 haplotype and a lower expression of TRL5.


Sebastiani, G., et al., Genomics 64(3):230-240 (2000).

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$ 80.00
Cat# BP1505b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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