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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Kremen Antibody (N-term) Blocking Peptide   

Kremen Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96MU8
Other Accession NP_114434
Clone Names 2110101
Peptide ID 2110101
Additional Information
Gene ID 83999
Other Names Kremen protein 1, Dickkopf receptor, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose, KREMEN1, KREMEN, KRM1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1527a was selected from the N-term region of human Kremen. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KREMEN, KRM1
Function Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Kremen is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.


Mao, B., et al., Nature 417(6889):664-667 (2002).Nakamura, T., et al., Biochim. Biophys. Acta 1518 (1-2), 63-72 (2001).

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$ 80.00
Cat# BP1527a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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