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Connexin 37 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P35212
Clone Names 2052010
Additional Information
Gene ID 2701
Other Names Gap junction alpha-4 protein, Connexin-37, Cx37, GJA4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1544b was selected from the C-term region of human GJA4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GJA4
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
Tissue Location Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium
Research Areas
Citations (0)

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Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.


Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Saito, T., et al., Int. J. Cancer 86(1):67-70 (2000).Boerma, M., et al., J. Intern. Med. 246(2):211-218 (1999).Krutovskikh, V., et al., Carcinogenesis 17(8):1761-1763 (1996).Reed, K.E., et al., J. Clin. Invest. 91(3):997-1004 (1993).

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$ 80.00
Cat# BP1544b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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