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Connexin 50 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P48165
Clone Names 2052203
Peptide ID 2052203
Additional Information
Gene ID 2703
Other Names Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1548a was selected from the N-term region of human GJA8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GJA8
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, gap junction
Tissue Location Eye lens.
Research Areas
Citations (0)

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GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.


Shiels, A., et al., Am. J. Hum. Genet. 62(3):526-532 (1998).Church, R.L., et al., Curr. Eye Res. 14(10):979-981 (1995).Church, R.L., et al., Curr. Eye Res. 14(3):215-221 (1995).

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$ 80.00
Cat# BP1548a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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