|Other Names||Hippocalcin-like protein 1, Calcium-binding protein BDR-1, HLP2, Visinin-like protein 3, VILIP-3, HPCAL1, BDR1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP1563a was selected from the N-term region of human VILIP3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.|
|Cellular Location||Membrane; Lipid-anchor|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
VILIP3 is a member of neuron-specific calcium-binding proteins family found in the retina and brain. It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1 proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of relevance for neuronal signalling in the central nervous system. There are two alternatively spliced transcript variants of this gene, with multiple polyadenylation sites. Transcript varian 1 utilizes a different exon and also lacks one exon in the 5' UTR, as compared to variant 2; thus, the encoded protein is the same.
Braunewell, K., et al., Dement Geriatr Cogn Disord 12(2):110-116 (2001).Bernstein, H.G., et al., J Neurocytol 28(8):655-662 (1999).Kobayashi, M., et al., Biochim. Biophys. Acta 1222(3):515-518 (1994).Hidaka, H., et al., Neurosci. Res. 16(2):73-77 (1993).Ivings, L., et al., Biochem. J. 363 (Pt 3), 599-608 (2002).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.