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GCAP2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UMX6
Clone Names 2010404
Peptide ID 2010404
Additional Information
Gene ID 2979
Other Names Guanylyl cyclase-activating protein 2, GCAP 2, Guanylate cyclase activator 1B, GUCA1B, GCAP2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP1568b was selected from the C-term region of human GCAP2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GCAP2
Function Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.
Cellular Location Cell membrane. Note=Membranes of outer segment
Tissue Location Retina. Cones and rod.
Research Areas
Citations (0)

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GCAP2, a member of the guanylin peptide family, is an endogenous activator of intestinal guanylate cyclase (GC-C). Uroguanylin is expressed in the stomach and intestine and uroguanylin, as well as guanylin, may be a potent physiological regulator of intestinal fluid and electrolyte transport.


Surguchov, A., et al., Genomics 39(3):312-322 (1997).Wiegand, R.C., et al., FEBS Lett. 311(2):150-154 (1992).de Sauvage, F.J., et al., Proc. Natl. Acad. Sci. U.S.A. 89(19):9089-9093 (1992).

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$ 80.00
Cat# BP1568b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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