P2RX2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UBL9 |
---|---|
Clone Names | 100507043 |
Gene ID | 22953 |
---|---|
Other Names | P2X purinoceptor 2, P2X2, ATP receptor, Purinergic receptor, P2RX2, P2X2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | P2RX2 |
---|---|
Synonyms | P2X2 |
Function | Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle. |
Cellular Location | Cell membrane; Multi-pass membrane protein Note=Localizes to the apical membranes of hair cells in the organ of Corti |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The product of this gene belongs to the family ofpurinoceptors for ATP. This receptor functions as a ligand-gatedion channel. Binding to ATP mediates synaptic transmission betweenneurons and from neurons to smooth muscle. Six transcript variantsencoding six distinct isoforms have been identified for this gene.
References
Allsopp, R.C., et al. J. Biol. Chem. 285(43):32770-32777(2010)Decker, D.A., et al. Neurogastroenterol. Motil. 22(8):901-908(2010)Coddou, C., et al. J. Neurosci. 29(39):12284-12291(2009)Pannek, J., et al. Spinal Cord 47(7):561-564(2009)Chaumont, S., et al. Sci Signal 1 (41), RA8 (2008) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.