|Other Names||Kunitz-type protease inhibitor 1, Hepatocyte growth factor activator inhibitor type 1, HAI-1, SPINT1, HAI1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14).|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of the Kunitzfamily of serine protease inhibitors. The protein is a potentinhibitor specific for HGF activator and is thought to be involvedin the regulation of the proteolytic activation of HGF in injuredtissues. Alternative splicing results in multiple variants encodingdifferent isoforms.
Chen, Y.W., et al. J. Biol. Chem. 285(41):31755-31762(2010)Kauppinen, J.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(9):2133-2142(2010)Nakamura, K., et al. Int. J. Oncol. 35(2):239-248(2009)Wang, J.K., et al. Am. J. Physiol., Cell Physiol. 297 (2), C459-C470 (2009) :Cheng, H., et al. Cancer Res. 69(5):1828-1835(2009)
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