GDF1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P27539 |
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Clone Names | 101109032 |
Gene ID | 2657 |
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Other Names | Embryonic growth/differentiation factor 1, GDF-1, GDF1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GDF1 |
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Function | May mediate cell differentiation events during embryonic development. |
Cellular Location | Secreted. |
Tissue Location | Expressed in the brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the bone morphogeneticprotein (BMP) family and the TGF-beta superfamily. This group ofproteins is characterized by a polybasic proteolytic processingsite that is cleaved to produce a mature protein containing sevenconserved cysteine residues. The members of this family areregulators of cell growth and differentiation in both embryonic andadult tissues. Studies in rodents suggest that this protein isinvolved in the establishment of left-right asymmetry in earlyembryogenesis and in neural development in later embryogenesis.This protein is transcribed from a bicistronic mRNA that alsoencodes the longevity assurance gene.
References
De Luca, A., et al. Clin. Genet. (2010) In press :Kaasinen, E., et al. Hum. Mol. Genet. 19(14):2747-2753(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Roessler, E., et al. Mol. Genet. Metab. 98 (1-2), 225-234 (2009) :Li, J., et al. Gynecol. Oncol. 114(1):89-93(2009)
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