|Other Names||Embryonic growth/differentiation factor 1, GDF-1, GDF1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May mediate cell differentiation events during embryonic development.|
|Tissue Location||Expressed in the brain.|
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This gene encodes a member of the bone morphogeneticprotein (BMP) family and the TGF-beta superfamily. This group ofproteins is characterized by a polybasic proteolytic processingsite that is cleaved to produce a mature protein containing sevenconserved cysteine residues. The members of this family areregulators of cell growth and differentiation in both embryonic andadult tissues. Studies in rodents suggest that this protein isinvolved in the establishment of left-right asymmetry in earlyembryogenesis and in neural development in later embryogenesis.This protein is transcribed from a bicistronic mRNA that alsoencodes the longevity assurance gene.
De Luca, A., et al. Clin. Genet. (2010) In press :Kaasinen, E., et al. Hum. Mol. Genet. 19(14):2747-2753(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Roessler, E., et al. Mol. Genet. Metab. 98 (1-2), 225-234 (2009) :Li, J., et al. Gynecol. Oncol. 114(1):89-93(2009)
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