|Other Names||Serine/threonine-protein phosphatase 4 regulatory subunit 3B, SMEK homolog 2, SMEK2, KIAA1387, PP4R3B, PPP4R3B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1387, PP4R3B, PPP4R3B|
|Function||Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers.|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions|
|Tissue Location||Moderately expressed in tissues and specific brain regions examined.|
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Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers.
Chowdhury, D., et al. Mol. Cell 31(1):33-46(2008)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)Gingras, A.C., et al. Mol. Cell Proteomics 4(11):1725-1740(2005)Mendoza, M.C., et al. Mol. Cell. Biol. 25(17):7839-7853(2005)
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