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CD200R1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8TD46
Clone Names 100528200
Peptide ID 100528200
Additional Information
Gene ID 131450
Other Names Cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1, CD200R1, CD200R, CRTR2, MOX2R, OX2R
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD200R1
Synonyms CD200R, CRTR2, MOX2R, OX2R
Function Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 2: Secreted.
Tissue Location Expressed in granulocytes, monocytes, most T- cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells.
Research Areas
Citations (0)

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This gene encodes a receptor for the OX-2 membraneglycoprotein. Both the receptor and substrate are cell surfaceglycoproteins containing two immunoglobulin-like domains. Thisreceptor is restricted to the surfaces of myeloid lineage cells andthe receptor-substrate interaction may function as a myeloiddownregulatory signal. Mouse studies of a related gene suggest thatthis interaction may control myeloid function in a tissue-specificmanner. Alternative splicing of this gene results in multipletranscript variants.


Luo, X.G., et al. Neurochem. Res. 35(4):540-547(2010)Mihrshahi, R., et al. J. Immunol. 183(8):4879-4886(2009)Koning, N., et al. J. Neuropathol. Exp. Neurol. 68(2):159-167(2009)Meuth, S.G., et al. J. Neuroimmunol. 194 (1-2), 62-69 (2008) :Wang, X.J., et al. J Neuroimmune Pharmacol 2(3):259-264(2007)

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$ 80.00
Cat# BP16040b
Availability: In Stock
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