PNLIP Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P16233 |
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Clone Names | 100528002 |
Gene ID | 5406 |
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Other Names | Pancreatic triacylglycerol lipase, PL, PTL, Pancreatic lipase, PNLIP |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PNLIP (HGNC:9155) |
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Function | Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones. |
Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the lipase gene family. Itencodes a carboxyl esterase that hydrolyzes insoluble, emulsifiedtriglycerides, and is essential for the efficient digestion ofdietary fats. This gene is expressed specifically in the pancreas.
References
Colin, D.Y., et al. Protein Eng. Des. Sel. 23(5):365-373(2010)Ranaldi, S., et al. Biochemistry 49(10):2140-2149(2010)Bourbon-Freie, A., et al. J. Biol. Chem. 284(21):14157-14164(2009)Ranaldi, S., et al. Biochemistry 48(3):630-638(2009)Colin, D.Y., et al. Biochem. Biophys. Res. Commun. 370(3):394-398(2008)
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