|Other Names||Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC, Transactivator HSM-1/2, NFYC|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'- CCAAT-3' box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes one subunit of a trimeric complexforming a highly conserved transcription factor that binds withhigh specificity to CCAAT motifs in the promoters of a variety ofgenes. The encoded protein, subunit C, forms a tight dimer with theB subunit, a prerequisite for subunit A association. The resultingtrimer binds to DNA with high specificity and affinity. Subunits Band C each contain a histone-like motif. Multiple transcriptvariants encoding different isoforms have been found for this gene.
Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010)Murai-Takeda, A., et al. J. Biol. Chem. 285(11):8084-8093(2010)Ceribelli, M., et al. J. Biol. Chem. 284(49):34189-34200(2009)Yamanaka, K., et al. Genomics 94(4):219-227(2009)Horikawa, Y., et al. Clin. Cancer Res. 14(23):7956-7962(2008)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.