|Other Names||40S ribosomal protein S14, RPS14|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit. Togetherthese subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. This gene encodes a ribosomalprotein that is a component of the 40S subunit. The protein belongsto the S11P family of ribosomal proteins. It is located in thecytoplasm. Transcript variants utilizing alternative transcriptioninitiation sites have been described in the literature. As istypical for genes encoding ribosomal proteins, there are multipleprocessed pseudogenes of this gene dispersed through the genome. InChinese hamster ovary cells, mutations in this gene can lead toresistance to emetine, a protein synthesis inhibitor. Multiplealternatively spliced transcript variants encoding the same proteinhave been found for this gene.
Oliva, E.N., et al. Eur. J. Haematol. 85(3):231-235(2010)Borze, I., et al. Cancer Genet. Cytogenet. 197(2):166-173(2010)Quarello, P., et al. Haematologica 95(2):206-213(2010)Valencia, A., et al. Blood 112 (3), 918 (2008) :Ebert, B.L., et al. Nature 451(7176):335-339(2008)
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