|Other Names||Carbamoyl-phosphate synthase [ammonia], mitochondrial, Carbamoyl-phosphate synthetase I, CPSase I, CPS1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.|
|Cellular Location||Mitochondrion. Nucleus, nucleolus|
|Tissue Location||Primarily in the liver and small intestine.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The mitochondrial enzyme encoded by this gene catalyzessynthesis of carbamoyl phosphate from ammonia and bicarbonate. Thisreaction is the first committed step of the urea cycle, which isimportant in the removal of excess urea from cells. The encodedprotein may also represent a core mitochondrial nucleoid protein.Three transcript variants encoding different isoforms have beenfound for this gene. The shortest isoform may not be localized tothe mitochondrion. Mutations in this gene have been associated withcarbamoyl phosphate synthetase deficiency, susceptibility topersistent pulmonary hypertension, and susceptibility tovenoocclusive disease after bone marrow transplantation.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Jia, P., et al. Schizophr. Res. 122 (1-3), 38-42 (2010) :Pekkala, S., et al. Hum. Mutat. 31(7):801-808(2010)Huo, R., et al. J. Biochem. Mol. Biol. 38(1):28-33(2005)Hoshide, R., et al. Genomics 28(1):124-125(1995)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.