|Other Names||P2Y purinoceptor 6, P2Y6, P2RY6|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
The product of this gene belongs to the family ofG-protein coupled receptors. This family has several receptorsubtypes with different pharmacological selectivity, which overlapsin some cases, for various adenosine and uridine nucleotides. Thisreceptor is responsive to UDP, partially responsive to UTP and ADP,and not responsive to ATP. Four transcript variants encoding thesame isoform have been identified for this gene. [provided byRefSeq].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Ben Yebdri, F., et al. Eur. J. Immunol. 39(10):2885-2894(2009)Wong, A.M., et al. Am. J. Respir. Cell Mol. Biol. 40(6):733-745(2009)Jiang, Y., et al. J. Immunol. 182(2):1129-1137(2009)Nishida, M., et al. EMBO J. 27(23):3104-3115(2008)
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