|Other Names||Cyclin-O, CCNO|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking.|
|Cellular Location||Cytoplasm. Note=Localizes to the apical part of cytoplasm|
|Tissue Location||Present in respiratory cells (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
This gene, which has a previous symbol of UNG2, waserroneously identified as a uracil DNA glycosylase in PubMed ID:2001396. A later publication, PubMed ID: 8419333, identified thisgene's product as a cyclin protein family member. The UNG2 term isalso used as a specific protein isoform name for the UNG gene(GeneID 7374), so confusion exists in the scientific literature andin some databases for these two genes.
Schmutz, J., et al. Nature 431(7006):268-274(2004)Muller, S.J., et al. J. Biol. Chem. 268(2):1310-1319(1993)Muller, S.J., et al. Biochim. Biophys. Acta 1088(2):197-207(1991)
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