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SNX17 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q15036
Clone Names 100528127
Peptide ID 100528127
Additional Information
Gene ID 9784
Other Names Sorting nexin-17, SNX17, KIAA0064
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNX17
Synonyms KIAA0064
Function Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Cellular Location Cytoplasm. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side
Research Areas
Citations (0)

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This gene encodes a member of the sorting nexin family.Members of this family contain a phox (PX) domain, which is aphosphoinositide binding domain, and are involved in intracellulartrafficking. This protein does not contain a coiled coil region,like some family members, but contains a B41 domain. This proteininteracts with the cytoplasmic domain of P-selectin, and mayfunction in the intracellular trafficking of P-selectin. [providedby RefSeq].


Lee, J., et al. J. Biol. Chem. 283(17):11501-11508(2008)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Czubayko, M., et al. Biochem. Biophys. Res. Commun. 345(3):1264-1272(2006)van Kerkhof, P., et al. EMBO J. 24(16):2851-2861(2005)

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$ 80.00
Cat# BP16064a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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