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Mouse Cdk20 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9JHU3
Clone Names 110316091
Peptide ID 110316091
Additional Information
Gene ID 105278
Other Names Cyclin-dependent kinase 20, CDK-activating kinase p42, CAK-kinase p42, CDK-related protein kinase PNQLARE, Cell cycle-related kinase, Cell division protein kinase 20, Cyclin-dependent protein kinase H, Cyclin-kinase-activating kinase p42, Cdk20, Ccrk, Cdch
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cdk20
Synonyms Ccrk, Cdch
Function Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity). Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling.
Cellular Location Nucleus. Cytoplasm. Cell projection, cilium
Research Areas
Citations (0)

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Background

Cdk20 is involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160' (By similarity). Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling.

References

Qiu, H., et al. J. Biol. Chem. 283(32):22157-22165(2008)Wohlbold, L., et al. Cell Cycle 5(5):546-554(2006)

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$ 80.00
Cat# BP16072c
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