|Other Names||Peripheral myelin protein 22, PMP-22, Growth arrest-specific protein 3, GAS-3, Pmp22, Gas-3, Gas3, Pmp-22|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||Gas-3, Gas3, Pmp-22|
|Function||Might be involved in growth regulation, and in myelinization in the peripheral nervous system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Schwann cells of the peripheral nervous system|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an integral membrane protein that is amajor component of myelin in the peripheral nervous system. Variousmutations of this gene are causes of Charcot-Marie-Tooth diseaseType IA, Dejerine-Sottas syndrome, and hereditary neuropathy withliability to pressure palsies.
Sahenk, Z., et al. Exp. Neurol. 224(2):495-506(2010)Coulpier, F., et al. J. Neurosci. 30(17):5958-5967(2010)Bai, Y., et al. J. Neurosci. 30(2):600-608(2010)Bremer, J., et al. PLoS ONE 5 (8), E12450 (2010) :Grossmann, K.S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(39):16704-16709(2009)
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