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EVI1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q03112
Clone Names 91009027
Peptide ID 91009027
Additional Information
Gene ID 2122
Other Names MDS1 and EVI1 complex locus protein EVI1, Ecotropic virus integration site 1 protein homolog, EVI-1, MECOM, EVI1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MECOM
Synonyms EVI1
Function Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis.
Cellular Location Nucleus. Nucleus speckle.
Research Areas
Citations (0)

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Background

EVI1 functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis.

References

Gomez-Benito, M., et al. Br. J. Cancer 103(8):1292-1296(2010)Meyer, T.E., et al. PLoS Genet. 6 (8) (2010) :Goyama, S., et al. Int. J. Hematol. 91(5):753-757(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Haas, K., et al. Genes Chromosomes Cancer 47(4):288-298(2008)

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$ 80.00
Cat# BP16088a
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