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EVI1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q03112 |
|---|---|
| Clone Names | 91009027 |
| Gene ID | 2122 |
|---|---|
| Other Names | MDS1 and EVI1 complex locus protein EVI1, Ecotropic virus integration site 1 protein homolog, EVI-1, MECOM, EVI1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MECOM (HGNC:3498) |
|---|---|
| Function | [Isoform 1]: Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis. |
| Cellular Location | Nucleus. Nucleus speckle. Cytoplasm |
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Provided below are standard protocols that you may find useful for product applications.
Background
EVI1 functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis.
References
Gomez-Benito, M., et al. Br. J. Cancer 103(8):1292-1296(2010)Meyer, T.E., et al. PLoS Genet. 6 (8) (2010) :Goyama, S., et al. Int. J. Hematol. 91(5):753-757(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Haas, K., et al. Genes Chromosomes Cancer 47(4):288-298(2008)
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