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HCRTR1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O43613
Clone Names 100525299
Peptide ID 100525299
Additional Information
Gene ID 3061
Other Names Orexin receptor type 1, Ox-1-R, Ox1-R, Ox1R, Hypocretin receptor type 1, HCRTR1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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The protein encoded by this gene is a G-protein coupledreceptor involved in the regulation of feeding behavior. Theencoded protein selectively binds the hypothalamic neuropeptideorexin A. A related gene (HCRTR2) encodes a G-protein coupledreceptor that binds orexin A and orexin B.


Peltonen, H.M., et al. Biochim. Biophys. Acta 1803(10):1206-1212(2010)Saus, E., et al. J Psychiatr Res 44(14):971-978(2010)Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :Turunen, P.M., et al. Br. J. Pharmacol. 159(1):212-221(2010)El Firar, A., et al. FASEB J. 23(12):4069-4080(2009)

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$ 80.00
Cat# BP16116c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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