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SEC14L2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O76054
Clone Names 100525306
Peptide ID 100525306
Additional Information
Gene ID 23541
Other Names SEC14-like protein 2, Alpha-tocopherol-associated protein, TAP, hTAP, Squalene transfer protein, Supernatant protein factor, SPF, SEC14L2, C22orf6, KIAA1186, KIAA1658
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEC14L2
Synonyms C22orf6, KIAA1186, KIAA1658
Function Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
Cellular Location Cytoplasm. Nucleus. Note=Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha- tocopherol
Tissue Location Widely expressed. Strong expression in liver, brain and prostate.
Research Areas
Citations (0)

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This gene encodes a cytosolic protein which belongs to afamily of lipid-binding proteins including Sec14p, alpha-tocopheroltransfer protein, and cellular retinol-binding protein. The encodedprotein stimulates squalene monooxygenase which is a downstreamenzyme in the cholesterol biosynthetic pathway. Alternativelyspliced transcript variants encoding different isoforms have beenidentified for this gene.


Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)Wang, X., et al. Cancer Invest. 27(10):971-977(2009)Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)Johnykutty, S., et al. Mod. Pathol. 22(6):770-775(2009)Wright, M.E., et al. Cancer Res. 69(4):1429-1438(2009)

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$ 80.00
Cat# BP16118a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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