|Other Names||Sterol O-acyltransferase 2, Acyl-coenzyme A:cholesterol acyltransferase 2, ACAT-2, Cholesterol acyltransferase 2, SOAT2, ACACT2, ACAT2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
|Tissue Location||Expression seems confined in hepatocytes and enterocytes.|
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SOAT2 plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Chen, S.N., et al. BMC Med. Genet. 10, 111 (2009) :
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