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MXD3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BW11
Clone Names 100528177
Peptide ID 100528177
Additional Information
Gene ID 83463
Other Names Max dimerization protein 3, Max dimerizer 3, Class C basic helix-loop-helix protein 13, bHLHc13, Max-associated protein 3, Max-interacting transcriptional repressor MAD3, Myx, MXD3, BHLHC13, MAD3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MXD3
Synonyms BHLHC13, MAD3
Function Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}
Research Areas
Citations (0)

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This gene encodes a member of the Myc superfamily of basichelix-loop-helix leucine zipper transcriptional regulators. Theencoded protein forms a heterodimer with the cofactor MAX whichbinds specific E-box DNA motifs in the promoters of target genesand regulates their transcription. Disruption of the MAX-MXD3complex is associated with uncontrolled cell proliferation andtumorigenesis. Transcript variants of this gene encoding differentisoforms have been described.


Barisone, G.A., et al. Cell Cycle 7(4):423-427(2008)Yun, J.S., et al. Mol. Cell. Biol. 27(23):8178-8189(2007)Hurlin, P.J., et al. Semin. Cancer Biol. 16(4):265-274(2006)Sommer, A., et al. J. Biol. Chem. 273(12):6632-6642(1998)

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$ 80.00
Cat# BP16120a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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