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GABPB1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q06547 |
|---|---|
| Clone Names | 100528040 |
| Gene ID | 2553 |
|---|---|
| Other Names | GA-binding protein subunit beta-1, GABP subunit beta-1, GABPB-1, GABP subunit beta-2, GABPB-2, Nuclear respiratory factor 2, Transcription factor E4TF1-47, Transcription factor E4TF1-53, GABPB1, E4TF1B, GABPB, GABPB2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GABPB1 |
|---|---|
| Synonyms | E4TF1B {ECO:0000303|PubMed:8441384}, GAB |
| Function | Transcription factor capable of interacting with purine rich repeats (GA repeats) (PubMed:8441384, PubMed:10675337, PubMed:8816484). Acts as a master regulator of nuclear-encoded mitochondrial genes (By similarity). |
| Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the GA-binding protein transcriptionfactor, beta subunit. This protein forms a tetrameric complex withthe alpha subunit, and stimulates transcription of target genes.The encoded protein may be involved in activation of cytochromeoxidase expression and nuclear control of mitochondrial function.The crystal structure of a similar protein in mouse has beenresolved as a ternary protein complex. Multiple transcript variantsencoding distinct isoforms have been identified for this gene.
References
Eynon, N., et al. Physiol. Genomics 41(1):78-81(2010)Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)Vercauteren, K., et al. J. Biol. Chem. 283(18):12102-12111(2008)Collins, P.J., et al. PLoS Genet. 3 (11), E208 (2007) :
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