|Other Names||GA-binding protein subunit beta-1, GABP subunit beta-1, GABPB-1, GABP subunit beta-2, GABPB-2, Nuclear respiratory factor 2, Transcription factor E4TF1-47, Transcription factor E4TF1-53, GABPB1, E4TF1B, GABPB, GABPB2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||E4TF1B, GABPB, GABPB2|
|Function||Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene.|
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This gene encodes the GA-binding protein transcriptionfactor, beta subunit. This protein forms a tetrameric complex withthe alpha subunit, and stimulates transcription of target genes.The encoded protein may be involved in activation of cytochromeoxidase expression and nuclear control of mitochondrial function.The crystal structure of a similar protein in mouse has beenresolved as a ternary protein complex. Multiple transcript variantsencoding distinct isoforms have been identified for this gene.
Eynon, N., et al. Physiol. Genomics 41(1):78-81(2010)Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)Vercauteren, K., et al. J. Biol. Chem. 283(18):12102-12111(2008)Collins, P.J., et al. PLoS Genet. 3 (11), E208 (2007) :
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