LTB4R2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NPC1 |
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Clone Names | 100528061 |
Gene ID | 56413 |
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Other Names | Leukotriene B4 receptor 2, LTB4-R 2, LTB4-R2, LTB4 receptor JULF2, Leukotriene B4 receptor BLT2, Seven transmembrane receptor BLTR2, LTB4R2, BLT2R, BLTR2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | LTB4R2 |
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Synonyms | BLT2R, BLTR2 |
Function | Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Widely expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
References
Kim, G.Y., et al. J. Immunol. 184(7):3946-3954(2010)Ryu, H.C., et al. J. Invest. Dermatol. 130(4):1095-1106(2010)Choi, J.A., et al. Carcinogenesis 31(4):543-551(2010)Cho, K.J., et al. Am. J. Respir. Cell Mol. Biol. 42(3):294-303(2010)Arcemisbehere, L., et al. J. Biol. Chem. 285(9):6337-6347(2010)
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