|Other Names||Leukotriene B4 receptor 2, LTB4-R 2, LTB4-R2, LTB4 receptor JULF2, Leukotriene B4 receptor BLT2, Seven transmembrane receptor BLTR2, LTB4R2, BLT2R, BLTR2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Widely expressed.|
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Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
Kim, G.Y., et al. J. Immunol. 184(7):3946-3954(2010)Ryu, H.C., et al. J. Invest. Dermatol. 130(4):1095-1106(2010)Choi, J.A., et al. Carcinogenesis 31(4):543-551(2010)Cho, K.J., et al. Am. J. Respir. Cell Mol. Biol. 42(3):294-303(2010)Arcemisbehere, L., et al. J. Biol. Chem. 285(9):6337-6347(2010)
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