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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   ASGR1 Antibody (N-term) Blocking Peptide   

ASGR1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P07306
Clone Names 100528078
Peptide ID 100528078
Additional Information
Gene ID 432
Other Names Asialoglycoprotein receptor 1, ASGP-R 1, ASGPR 1, C-type lectin domain family 4 member H1, Hepatic lectin H1, HL-1, ASGR1, CLEC4H1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASGR1
Synonyms CLEC4H1
Function Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Cellular Location Isoform H1a: Membrane; Single-pass type II membrane protein
Tissue Location Expressed exclusively in hepatic parenchymal cells
Research Areas
Citations (0)

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Partially deglycosylated plasma glycoproteins andimmunoglobulin IgA2 allotypes are efficiently and specificallyremoved from circulation by a receptor-mediated process. Theasialoglycoprotein receptor binds to desialylated(galactosyl-terminal) glycoproteins. It transports theseglycoproteins via a series of membrane vesicles and tubules to anacidic-sorting organelle where the receptor and ligand dissociate.Then the receptor is recycled back to the cell surface and theligand is transported to the lysosomes for degradation.Alternatively spliced transcript variants encoding distinctisoforms have been identified.


Yang, J., et al. Arch. Virol. 155(6):881-888(2010)Liu, J., et al. PLoS ONE 5 (9), E12934 (2010) :Sorensen, A.L., et al. Blood 114(8):1645-1654(2009)Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Yik, J.H., et al. J. Biol. Chem. 277(43):40844-40852(2002)

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$ 80.00
Cat# BP16133a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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