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RAC3 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P60763
Clone Names 100528117
Peptide ID 100528117
Additional Information
Gene ID 5881
Other Names Ras-related C3 botulinum toxin substrate 3, p21-Rac3, RAC3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAC3
Function Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
Cellular Location Cytoplasm. Endomembrane system. Cell projection, lamellipodium. Cytoplasm, perinuclear region. Cell membrane. Cytoplasm, cytoskeleton. Note=Membrane-associated when activated. Colocalizes with NRBP to endomembranes and at the cell periphery in lamellipodia. Colocalized with CIB1 in the perinuclear area and at the cell periphery
Tissue Location Highest levels in brain, also detected in heart, placenta and pancreas
Research Areas
Citations (0)

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The protein encoded by this gene is a GTPase which belongsto the RAS superfamily of small GTP-binding proteins. Members ofthis superfamily appear to regulate a diverse array of cellularevents, including the control of cell growth, cytoskeletalreorganization, and the activation of protein kinases. [provided byRefSeq].


Hajdo-Milasinovic, A., et al. J. Cell. Sci. 122 (PT 12), 2127-2136 (2009) :Lozano, E., et al. J. Cell. Sci. 121 (PT 7), 933-938 (2008) :Hajdo-Milasinovic, A., et al. J. Cell. Sci. 120 (PT 4), 555-566 (2007) :Watabe-Uchida, M., et al. Neuron 51(6):727-739(2006)Orioli, D., et al. Mol. Biol. Cell 17(5):2391-2400(2006)

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$ 80.00
Cat# BP16138c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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