|Other Names||Leukocyte elastase inhibitor, LEI, Monocyte/neutrophil elastase inhibitor, EI, M/NEI, Peptidase inhibitor 2, PI-2, Serpin B1, SERPINB1, ELANH2, MNEI, PI2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||ELANH2, MNEI, PI2|
|Function||Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also functions as a potent intracellular inhibitor of granzyme H.|
|Cellular Location||Cytoplasm. Cytoplasmic granule|
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Provided below are standard protocols that you may find useful for product applications.
SERPINB1 regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3.
Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Ahmed, M., et al. J. Proteome Res. 4(3):931-940(2005)Mungall, A.J., et al. Nature 425(6960):805-811(2003)Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)
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